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Target Screening & Profiling




Our target profiling services provide selectivity testing of compounds against kinases and phosphatases and functional cell-based GPCR and ion channel compound profiling. Whether optimizing lead compounds or investigating cardiac safety or off-target effects, we provide the expert services that can advance your discovery.

Complementing our services is a broad portfolio of kinases, phosphatases and enzyme assays built upon the cell signaling expertise of Upstate. Our innovative GPCR and ion channel cell lines and reagents speed assay development and advance discovery with robust, reliable quality and technical support.

MILLIPORE Voted,
"Most preferred outsourced profiling supplier and the most trusted fee-for-service supplier to provide rapid turnaround and reliable results."
- Kinase Screening & Profiling Trends,
HTStec Limited, 2008


GPCR Target Solutions

We have developed proprietary technologies to enhance the functional expression of GPCRs while allowing for a single functional readout regardless of G protein-coupling status. This technology is the foundation of Millipore’s robust and reliable GPCR products and services.
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Ion Channel Target Solutions

Millipore has created an extensive portfolio of recombinant PrecisION cell lines expressing a variety of biologically-relevant ion channels using both manual and automated patch clamp technology on the IonWorks HT/Quattro system.
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Kinase & Phosphatase Target Solutions

Through partnerships with thought leaders in kinase research, and development of internal expertise and talent, we now provide the most comprehensive selection of enzymes in the industry.
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FlexLab Services

We offer custom protein production for kinases, phosphatases and protein substrates and custom cell line development for GPCRs and Ion Channels.
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Safety & Liability Screening

Millipore offers a unique cross-target service panel for early drug discovery screening against a liability-focused functional assay panel of GPCRs, ion channels, kinases and phosphatases.
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